CEVAMEC® 1 % INJECTABLE SOLUTION

Do not slaughter cattle or sheep for human consumption within 21 days of last treatment.

Do not use in lactating cattle where milk or milk products are used for human consumption.

Do not use in dairy cattle within 28 days of calving.

Do not use intramuscularly or intravenously.

Keep out of reach of children, uninformed persons and animals.

Although this remedy has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

Do not eat, drink or smoke while handling the product.

Store bottle in carton to protect from light.

Wash hands thoroughly after use.

Cattle should be vaccinated against Clostridial infections (eg Black quarter).

Sheep should be vaccinated against pulpy kidney (entero-toxaemia) before treatment.

Temporary discomfort has been observed in animals following subcutaneous injection. The pain reaction is sometimes intense, but usually transient. A low incidence of soft tissue swelling at the injection site has been observed. These reactions disappeared without treatment.

Subcutaneous route: Cattle

CEVAMEC 1 % Injectable Solution should be given only by subcutaneous injection at the approved dosage level of 200 µg Ivermectin per kilogram of body mass.  Each mℓ contains 10 mg of Ivermectin, sufficient to treat 50 kg of body mass. 

Body mass (kg): Up to 50 kg = Dose volume (ml) 1

Body mass (kg): 51-100 = Dose volume (ml) 2

Body mass (kg): 101-150 = Dose volume (ml) 3

Body mass (kg): 151-200 = Dose volume (ml) 4

Body mass (kg): 201-250 = Dose volume (ml) 5

Body mass (kg): 251-300 = Dose volume (ml) 6

Body mass (kg): 301-350 = Dose volume (ml) 7

Body mass (kg): 351-400 = Dose volume (ml) 8

Body mass (kg): 401-450 = Dose volume (ml) 9

Body mass (kg): 451-500 = Dose volume (ml) 10

Body mass (kg): 501-550 = Dose volume (ml) 11

Body mass (kg): 551-600 = Dose volume (ml) 12

CATTLE

CEVAMEC 1% Injection Solution is to be given by subcutaneous injection only. Do not administer intramuscularly or intravenously. In cattle inject under the loose skin in front of or behind the shoulder. Use of a 16-gauge 2,0-cm needle is suggested. Use sterile equipment and follow aseptic procedures.

Appropriate vaccination precautions should be taken in areas where the risk of Clostridial infections of cattle such as black quarter (sponssiekte) and malignant oedema are present.

SHEEP

CEVAMEC 1% Injectable Solution is to be given by subcutaneous injection only. Do not administer intramuscularly or intravenously. The solution may be administered with any standard automatic or single-dose equipment. Use aseptic technique. The loose skin behind the shoulder, the skin under the foreleg (axilla) and the inside of the thigh are suitable sites for administration. Ensure that the needle is carefully inserted and that the solution does not leak from the injection site. In wooly sheep, ensure that the needle has penetrated the wool and skin before delivering the dose.

Sheep scab is a notifiable disease and all suspected outbreaks must be reported to the nearest state veterinary office. Treatment must be under government supervision.

For treatment of sheep scab outbreaks two treatments with an interval of seven days are recommended. Each dose is 1 mℓ / 50 kg (200 µg / kg).

NOTE: When treating an outbreak of sheep scab it is essential that:

1. All sheep on the farm must be accurately treated with the correct dose and marked after treatment.
2. All animals must be checked 7- 10 days after treatment and any animals not marked must be treated.
3. Care must be taken that the full dose is administered to each sheep.

An autumn treatment will kill third stages of nasal worm and a spring treatment will offset new infestations of this parasite.

A treatment in late autumn will remove roundworm burdens as well as first infestations of those roundworm species stimulated by cooler weather conditions. The spring "off-shears" treatment will remove roundworm burdens which have built up during the winter and early spring infestations stimulated by the first rains. This will contribute to reducing the contamination of "clean" summer grazing.

Instructions for use with automatic dosing equipment (250 mℓ and 500 mℓ packs):

• Disinfect all needles and syringes before using by boiling in clean water for 15 to 20 minutes.
• Boiled needles should be stored in an antiseptic solution before use and changed frequently when injecting animals.
• Remove the draw-off assembly from the sterile pack.
• Handle carefully to avoid contamination.
• Connect the plastic tube firmly to dosing syringe.
• Remove cap from bottle and disinfect rubber stopper with methylated spirits or other suitable chemical disinfectant.
  • Hold bottle upright and fully insert draw-off needle into center of rubber stopper.
  • Hang bottle comfortably in inverted position from neck, shoulder or belt.
  • Use attachment tapes provided.
  • Gently prime injector.
  • Equipment is now ready for use.
  • After use, remove draw-off assembly from pack and flush out entire apparatus with water before storing.
    • If connecting tube is re-used, it should be boiled for 15 to 20 minutes before use along with the injecting syringe and needles.
    • Store partly used bottle in carton to protect from light.
    • Do not re-use empty bottles.

Studies indicate that when Ivermectin comes in contact with the soil, it readily and compactly binds to the soil and becomes inactive over time.

Drug containers and any residual contents should be disposed of safely (eg by burying or incinerating), as residual Ivermectin may adversely affect fish and certain water-borne organisms.