For animal use only.

Clostrivax B+ is an adjuvanted multi-component vaccine for the active immunisation of cattle against diseases caused by Clostridium perfringens type A (enterotoxaemia, gas gangrene, sudden death syndrome), C. botulinum types C and D (botulism), C. novyi type A (swollen head), C. novyi type B (black disease, infectious necrotic hepatitis), C. chauvoei (black leg, black quarter), C. sordellii (sudden death syndrome), C. septicum (malignant oedema, braxy) and Mannheimia haemolytica type A1 (pneumonia) and Bacillus anthracis (anthrax).

Anthrax is a controlled disease in terms of the Animal Diseases Act (Act no. 35 of 1984) and any suspicion or confirmation of the disease must be reported to the responsible state veterinarian immediately.

COMPOSITION PER DOSE (2 ml)

Clostrivax B+ contains toxoids from C. perfringens type A, C. botulinum types C and D, C. novyi types A and B, C. sordellii, C. septicum, M. haemolytica type A1 leukotoxin, formalin inactivated C. chauvoei anacultures and live uncapsulated avirulent spores of B. anthracis Sterne 34F2.

STORAGE

Store and transport refrigerated between 2°C and 8°C. Do not freeze. Protect from high temperatures and direct sunlight during vaccination. Do not use after the expiry date printed on the container. Use immediately after opening the vial.

DIRECTIONS FOR USE - USE ONLY AS DIRECTED

Consult your veterinarian before use.
Simple inversion of the vial prior to and during use is adequate to mix all components.
Inject cattle subcutaneously on the side of the neck. DO NOT deviate from the recommended route and injection site location.
Animals must receive a full vaccination schedule before the period of highest risk.
Ensure that all animals are vaccinated.
It is essential to adhere to the vaccination programme to maintain a satisfactory immune response.
Calves may be vaccinated from 2 months of age and older.
Cows that were vaccinated in the past 12 months must be vaccinated 2-6 weeks before calving is due to commence. This provides passive protection to the calf, via colostrum, for up to 8 weeks.
Revaccinate annually with a single dose (2 ml).

DOSAGE

Administer a single dose (2 ml) subcutaneously, on the side of the neck only. DO NOT deviate from the recommended route and injection site location.
A booster dose of 2 ml is required 3-4 weeks later, with either Clostrivax B+ or Clostrivax B.
Vaccination and booster must be completed 2 months prior to the outbreak season.

PACKING SIZE AND ORDERING CODE

100 ml (LVS06120)

Reg. no. G4484 (36/1947)

Reg. holder: Vetvax (Pty) Ltd, Reg. no. 2004/035302/07, 442 Rigel Avenue South, Erasmusrand, Pretoria | Tel. 012 349 2772

Clostrivax B+ | Cattle Vaccine

Withdrawal period: Do not slaughter animals for human consumption within 21 days of vaccination.

Vaccinate healthy animals only.

DO NOT mix with any other vaccine or immunological product.

Avoid direct contact with the product, to prevent self-injection, or contamination of the eyes or skin. If contact occurs, rinse affected area repeatedly with clean water. Medical advice should be sought in the event of accidental exposure.

Do not over- or under-dose the vaccine.

Usually no marked reactions follow vaccination, although a transient swelling may appear at the site of inoculation, and some animals may show a moderate rise of temperature for one or two days.

Ensure that marketed animals do not have local reacions (swellings) at the site of vaccine administration, or elevated temperature reactions (fever) as this may result in the condemnation of the carcasses.

Use the entire contents of the vial once opened.

Do not use in animal species other than those indicated.

Do not administer to animals in poor or extremely poor body condition.

KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.

Although this product has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

Simultaneous administration of antibiotics to vaccinated animals is contraindicated as the antibiotic will interfere with the vaccine.

Antibiotics should not be given several days before and after vaccination.

Clostrivax B+ is safe to use in heifers and cows in all trimesters of pregnancy or calves nursing from pregnant cows.
Follow aseptic procedures. Clean and sterilise all vaccination equipment (containers, syringes and needles) prior to and during use to prevent contaminating the contents of the vial.

Do not use the contents of damaged vials.

Wear protective clothing, masks, gloves etc. according to hazard standards.

Avoid contact with skin, eyes and mouth.

Do not eat, drink or smoke whilst handling the product.

Do not store partially used vials and dispose of all containers and disposable equipment after use, in accordance with the National Environmental Management: Waste Act (Act no. 59 of 2008).

Do not contaminate rivers, dams or any water sources with containers or waste.

Local reactions may occur in some animals at the injection site. They will disappear after a few days. If you notice any serious effects not mentioned here, please inform your veterinarian.

Wash and disinfect hands with a disinfectant after vaccination.

Clostrivax B+ | Cattle Vaccine

Warnings

Precautions